Thanks for posting this - interesting bottle.
This one has two big upsides - it is a CURE which is a focus for lots of collectors, and it is from a small town in the Midwest. One cannot be an expert on every bottle out there but I suspect, like you seem to, that since this is from a small town, it is probably a scarce item. Could be. It probably is going to take an Iowa collector to help further on this, esp. with value. I could only provide a shoot-from-the-hip guesstimate.
And, in case you did not see this, here is at least a mention of your bottle: https://www.fohbc.org/wp-content/uploads/2014/07/Ioway_MedicinesP2.pdf
